Bruker Introduces Fast BioAFM for Automated Mechanobiology | Your money

BERLIN – (BUSINESS WIRE) – Dec. 20 2021–

Bruker today announced the release of the JPK NanoWizard® V BioAFM, a new system that marks a milestone in automation and ease of use for atomic force microscopy research in the life sciences. NanoWizard V is a very fast and automated BioAFM that can optionally be fully integrated with advanced optical microscopes. It enables rapid quantitative mechanical measurements and dynamic analysis on samples ranging in size from submolecular size to cells and tissues. The automated configuration, alignment and readjustment of system parameters opens up new possibilities for long-term self-regulatory experiments on mechanobiological dynamics.

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The JPK NanoWizard V BioAFM (Photo: Business Wire)

“The system’s promised speed and resolution, ease of use and down to millimeter capabilities make it a radical change for AFM investigations in nanomedical and biomedical applications,” said Dr. David Martinez Martin, master of conferences in Biomedical Engineering and Co. -President of the Sensors and Diagnostics group of the Nanohealth Network at the University of Sydney, Australia. Dr. Martinez Martin’s research focuses on the discovery of new biomarkers for health and disease, as well as cell physiology.

“We believe that the NanoWizard V is the most advanced BioAFM, and it combines three important innovations in a single system: rapid quantitative mechanobiological measurements, rapid scanning AFM and automation that requires minimal user intervention, ”added Dr Heiko Haschke, director of Bruker’s BioAFM. “Over the past decade, we have accumulated a wealth of experience in quantitative nanomechanics using PeakForce Tapping® and Quantitative Imaging (IQ) modes. By bringing together the best aspects of both in our new PeakForce-QITM mode, we enable novices and experts alike to perform high-resolution BioAFM quantitative mechanobiology experiments. We expect this new system to contribute significantly to a more complete understanding of dynamic cellular processes and correlated molecular mechanisms.

About the JPK NanoWizard V BioAFM

JPK NanoWizard V is the latest generation of Bruker’s industry-leading BioAFMs. It has been optimized for high spatiotemporal resolution with a large scanning area, flexible experiment design, and exceptional integration with advanced optical microscope systems. Its PeakForce-QI mode enables fast and flexible quantitative nanomechanical measurements, greatly expanding AFM’s capabilities in terms of speed and resolution. NanoWizard V features new scanner and sensor technologies and state-of-the-art control software that encompasses an intuitive, work-flow-based Graphical User Interface (GUI) to ensure real and easy-to-use AFM operation. The system includes JPK’s signature high-speed, high-performance Vortis 2 control electronics, advanced digital control, and new software concepts that enhance its multi-parameter imaging capabilities and data processing routines. Using motorized mapping and DirectOverlay, DirectTiling, and ExperimentPlanner functionality, positions and measurements can be configured to run and realign automatically, ensuring fast sample observation and maximum force sensitivity. Combined with new automated hardware features and a wide range of liquid cell and temperature control options, the JPKNanoWizard V allows users of all skill levels to fully focus on their experiences and is therefore the ideal tool for multi-user environments or imaging facilities.

About JPK BioAFM

JPK joined Bruker in July 2018, bringing in-depth expertise in living cell imaging, cell mechanics, adhesion and molecular force measurements, optical trapping, and biological stimulus-response characterization to Bruker’s global infrastructure. and developing and supporting established instruments. JPK BioAFM takes full advantage of the best of both stories to provide microscopy instrumentation for biomolecular and cellular imaging, as well as force measurements on single molecules, cells and tissues. To learn more about Bruker’s Biological Research AFMs, please visit:

About Bruker Corporation (NASDAQ: BRKR)

Bruker enables scientists to make groundbreaking discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific instruments and valuable analytical and diagnostic solutions enable scientists to explore life and materials at the molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker enables innovation, improved productivity and customer success in molecular research in the life sciences, in applied and pharmaceutical applications, in microscopy and nanoanalysis, and in applications industrial, as well as in cell biology, preclinical imaging, research in clinical phenomena and proteomics and clinical microbiology. For more information, please visit:

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CONTACT: Investor:

T: +1 (978) 663-3660 x1479

E: [email protected] Media:

Dr Gabriela Bagordo

BioAFM communication manager

Bruker Nano GmbH

T: +49 (30) 670990 7500

E: [email protected]



SOURCE: Bruker Corporation

Copyright Business Wire 2021.

PUB: 12/20/2021 7:00 a.m. / DISC: 12/20/2021 7:02 a.m.

Copyright Business Wire 2021.

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